BACKGROUND:Toxic Shock Syndrome (TSS) is characterized by fever, rash, hypotension, constitutional symptoms, and multi-organ involvement and is caused by Staphylococcus aureus enterotoxins such as Staphylococcal Enterotoxin B (SEB).SEB binds to the MHC-IIalpha chain and is recognized by the TCRbeta chain of the Vbeta8 TCR(+) T cells.The binding of
Abstract Background Bed nets reduce malaria-related illness and deaths, by forming a protective barrier around people sleeping under them.When impregnated with long-lasting insecticide formulations they also repel or kill mosquitoes attempting to feed upon sleeping humans, and can even suppress entire populations of malaria vectors that feed predom
Industrialization and population growth lead to changes in the quantity as well as composition of the solid waste produced in a city.This further leads to environmental pollution and deterioration of soil as well as groundwater quality in many cities.Improper management of solid waste results in several challenges for the city inhabitants, predomin
Objectives/Goals: This study aimed to investigate the role of artificial intelligence (AI) in translational science, including personalization of interventions and drug development.Methods/Study Population: A comprehensive literature search was conducted via PubMed, the Cumulative Index for Nursing and Allied Health Literature (CINAHL), Cochrane Li
Noncoding RNAs control critical cellular processes, although their contribution to disease remains largely unexplored.Dyskerin associates with hundreds of H/ACA small RNAs to generate a multitude of functionally distinct ribonucleoproteins (RNPs).The DKC1 gene, encoding dyskerin, is mutated in the multisystem disorder X-linked dyskeratosis congenit